The story of the IUPHAR-Ed Core Concepts of Pharmacology Project

Launched in 2021, this ambitious project aims to transform pharmacology education by helping students and educators to focus on the knowledge that matters.

The Core Concepts of Pharmacology Education Project

A project of the International Union of Basic and Clinical Pharmacology Education Section (IUPHAR-ED)

Why core concepts?

Pharmacology students around the world struggle with content overload and often have reduced curricular time devoted to pharmacology

A focus on core concepts helps students develop pharmacology knowledge structures – deep applied understanding of the foundational, enduring, useful, complex and challenging ideas that underpin how medicines work

Educators around the world are now using the core concepts as anchors for their pharmacology curricula – working to ensure that graduates retain the ability to apply these concepts years after their graduation

See below for some publications that articulate the project rationale and aims

Guilding, Clare, et al. “Developing an international concept‐based curriculum for pharmacology education: the promise of core concepts and concept inventories.” British Journal of Clinical Pharmacology 91.8 (2025): 2142-2150.

Guilding, Clare, et al. “Reimagining pharmacology education.” Pharmacological reviews (2026): 100126.

First, we identified, defined and unpacked the 24 core core concepts that all students who have studied pharmacology should remember, understand and apply

Then we studied student understanding and misconceptions of our core concepts

Next we designed studies that asked students to explain what each core concept meant to them and then asked them to apply the concept in a simple novel scenario. We have analysed responses from over 1000 students so far for 16 of the 24 concepts.

We published two papers in 2025 that show the outcomes of those analyses for Pharmacokinetic (PK) and pharmacodynamic (PD) concepts

PK: Babey, Anna-Marie, et al. “Evaluating student understanding of core pharmacokinetic concepts.” European Journal of Pharmacology 990 (2025): 177256.

PD: Kelly-Laubscher, Roisin, et al. “Evaluating student understanding of pharmacodynamics core concepts.” European Journal of Pharmacology 990 (2025): 177257.

In parallel, Adeladlew Netere worked with many pharmacology educators to develop a pharmacology concept inventory (PCI) that tests student understanding of our core concepts

The International Core Concepts of Pharmacology Education Project is endorsed and adopted by IUPHAR education section. This website is administered by Monash University Faculty of Pharmacy and Pharmaceutical Sciences.

We acknowledge the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their Elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.

© International Core Concepts of Pharmacology Education Project 2022